Jaehoon Sim

Postdoctoral Researcher


Education:

  University of Pennsylvania, 2017-present
Postdoctoral Researcher with Professor Gary A. Molander

Research Professor Cha University, 2017


Ph.D. Seoul National University, Korea, 2010-2016
“Total Synthesis of Dysodensiol F via Versatile Synthetic Strategy for Guaiane Sesquiterpenoids” with Prof. Young-Ger Suh

B.S. College of Pharmacy, Seoul National University, Korea, 2010
Current Research:
    Photoredox Cross-Coupling

Publications:
  • Total Synthesis of (+)-Brasilenyne via Concise Construction of Oxonane Framework Containing 1,3-cis,cis-Diene Lim, C.; Ahn, J.; Sim, J.; Yun, H.; Hur, J.; An, H.; Jang, J.; Lee, S.; Suh, Y.-G. Chem. Commun., 2018, Advance Article.
  • Nicrophorusamides A and B, Antibacterial Chlorinated CyclicPeptides from a Gut Bacterium of the Carrion Beetle Nicrophorusconcolor Shin, Y.; Bae, S.; Sim, J.; Hur, J.; Jo, S.; Shin, J.; Suh, Y.-G.; Oh, K.-B.; Oh, D.-C. J. Nat. Proc., 2017, 80 2962.
  • A highly stereoselective and efficient synthesis of enantiomerically pure sitagliptin Kang, S. K.; Cho, G. H.; Leem, H. J.; Soh, B. K.; Sim, J.; Suh, Y.-G. Tetrahedron: Asymmetry, 2017, 28, 34.
  • Construction of the Azacyclic Core of Tabernaemontanine-Related Alkaloids via Tandem Reformatsky−Aza-Claisen Rearrangement Suh, Y.-G.; Lim, C.; Sim, J.; Lee, J. K.; Surh, Y.-J.; Paek, S.-M. J. Org. Chem., 2017, 82, 1464.
  • Practical and efficient synthesis of gefitinib through selective O-alkylation: A novel concept for a transient protection group Kang, S. K.; Lee, S. W.; Woo, D.; Sim, J.; Suh, Y.-G. Synth. Commun., 2017, 47, 1990.
  • Practical and Sustainable Synthesis of Optically Pure Levocabastine, a H1 Receptor Antagonist Kang, S. K.; Nam, D. H.; Ahn, J.; Lee, J.; Sim, J.; Lee, J.; Suh, Y.-G. Molecules, 2017, 22, 1971.
  • Divergent synthetic route to new cyclopenta[c]pyran iridoids: syntheses of jatamanin A, F, G and J, gastrolactone and nepetalactone Sim, J.; Yoon, I.; Yun, H.; An, H.; Suh, Y. G. Org. Biomol. Chem., 2016, 14, 1244.
  • Studies on The Aza-Claisen Rearrangement of 7 to 9-Membered Vinylazacycle Kim, S.-H.; Lee, W.-I.; Kim, S.-M.; Jung, J.-K.; Jang, J.; Sim, J.; Jung, J.-W.; Suh, Y.-G. Heterocycles, 2016, 92, 886.
  • Efficient strategy for the stereoselective synthesis of 2,3-disubstituted benzo[a]quinolizidine alkaloids: concise synthesis of protoemetinol Moon, H.; An, H.; Sim, J.; Kim, K.; Paek, S. M.; Suh, Y. G. Tetrahedron Lett., 2016, 92, 886.
  • Synthesis and Structural Elucidation of Macrosphelide J and K An, H.; Kim, S. H.; Kim, H.; Kim, K.; Sim, J.; Jang, J.; Paek, S. M.; Suh, Y. G.; Yun, H. Heterocycles, 2015, 91, 970.
  • Total synthesis of (-)-deguelin via an iterative pyran-ring formation strategy Lee, S.; An, H.; Chang, D.-J.; Jang, J.; Kim, K.; Sim, J.; Lee, J.; Suh, Y.-G. Chem. Commun., 2015, 51, 9026.
  • Design and synthesis of a macrosphelide A-biotin chimera Yun, H.; Sim, J.; An, H.; Lee, J.; Lee, H. S.; Shin, Y. K.; Paek, S.-M.; Suh, Y.-G. Org. Biomol. Chem., 2014, 12, 7127.
  • Microwave-assisted synthesis of 3-substituted indoles via intramolecular areneealkene coupling of o-iodoanilino enamines Lee, W.-I.; Jung, J.-W.; Sim, J.; An, H.; Suh, Y.-G. Tetrahedron , 2013, 69, 7211.
  • Achiral auxiliary-assisted chiral transfer via microwave-accelerated aza-Claisen rearrangement: a short synthesis of (+)-1-hydroxyquinolizidinone Sim, J.; Yun, H.; Jung, J. W.; Lee, S.; Kim, N. J.; Suh, Y. G. Tetrahedron Lett. , 2012, 53, 4813.
  • Asymmetric formal synthesis of schulzeines A and C Jang, J.; Jung, J.-W.; Ahn, J.; Sim, J.; Chang, D.-J.; Kim, D.-D.; Suh, Y.-G. Org. Biomol. Chem. , 2012, 10, 5202.
  • Asymmetric Syntheses of 1-Deoxy-6,8a-di-epi-castanospermine and 1-Deoxy-6-epi-castanospermine Yun, H.; Kim, J.; Sim, J.; Lee, S.; Han, Y. T.; Chang, D.; Kim, D.; Suh, Y.-G. J. Org. Chem. , 2012, 77, 5389.